VTU Bio-Technology 3rd Semester Syllabus

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Download VTU Bio-Technology Syllabus Soft Copy

VTU Bio-Technology 3rd Semester Syllabus

ENGINEERING MATHEMATICS – III
CODE: 10 MAT 31

IA Marks: 25
Hrs/Week: 04 Exam Hrs: 03
Total Hrs: 52 Exam Marks:100

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INTRODUCTION TO UNIT OPERATIONS
Subject code : 10BT-32

I.A Marks : 25
Hrs./Week : 04 Exam Hrs. : 03
Total Hours : 52 Exam Marks : 100

PART A

UNIT 1:
DIMENSIONAL ANALYSIS
Units, Dimensions, Basic and Derived units, Dimensionless numbers – Reynold’s number, Nusselt number, Prandtl number, Grashoff number, Rayleigh method, Buckingham’s pi theorem – problems on natural and forced convection. 04 Hours

UNIT 2:
FLUID MECHANICS
Fluid definition and classification (Types of fluids – Newtonian and Non Newtonian); U – tube manometer, Types of flow – laminar and Turbulent; Reynolds experiment; Basic equations of fluid flow – Continuity equation , Euler’s equation and Bernoulli equation; Flow through circular and non circular conduits – Hagen Poiseuille equation (no derivation); Flow past immersed bodies – application of Kozney-Karmen equation; Flow through stagnant fluids – theory of Settling and Sedimentation – Equipments. Conceptual numericals. 12 Hours

UNIT 3:
FLOW MEASUREMENTS
Flow measurements – Orifice meter, Venturimeter, Rotameter. Pumps – types of pumps (Centrifugal & Reciprocating pumps), application of Bernoulli’s equation for Energy
calculations in pumps. Conceptual numericals. 04 Hours

UNIT 4:
MECHANICAL OPERATIONS
Size reduction – laws, working principle of ball mill. Sieve analysis – Conceptual numericals of differential and cumulative analysis. Mixing – types of mixers (ribbon and muller mixer), power number and power number calculation; Filtration – constant rate and constant pressure filtration, filtration equipments (plate and frame, rotary drum). 06 Hours

PART B

UNIT 5:
CONDUCTIVE HEAT TRANSFER
Modes of heat transfer; Conduction – steady state heat conduction through uni-layer and multilayer walls, cylinders; Insulation, critical thickness of insulation. 04 HOURS

UNIT 6:
CONVECTIVE HEAT TRANSFER
Forced and Natural convection; Condensation – film wise and drop wise (no derivation); Heat transfer equipments – double pipe heat exchanger, shell and tube heat exchanger. Conceptual numericals. 09 Hours

UNIT 7:
BASICS OF MASS TRANSFER
Diffusion – Fick’s law of diffusion. Measurement of diffusivity, Mass transfer coefficients and their correlations 04 Hours

UNIT 8:
MASS TRANSFER OPERATIONS
Distillation – Methods of distillation, distillation of binary mixtures using McCabe Thiele method; leaching equipments (belt extraction and basket extraction). Conceptual numericals. 09 Hours

TEXT BOOKS / REFERENCE BOOKS
Refer Syllabus Copy

HUMAN PHYSIOLOGY
Subject code : 10BT-33

I.A Marks : 25
Hrs./Week : 04 Exam Hrs. : 03
Total Hours : 52 Exam Marks : 100

PART A

UNIT 1:
SKELETAL & MUSCULAR SYSTEM
Cartilage and bone; Comparison between cartilage and bone; Functions of skeletal system; Joints; Muscles of limb movement. Principal types of muscles; General properties of muscles; Mechanism of muscle contraction and relaxation, Red and white muscle fibers. 07 Hours

UNIT 2:
CIRCULATORY SYSTEM
Structure, Composition and functions of blood. Blood Groups and Rh factor. Immunity and antibody formation. Heart and Blood vessels, Arterial and Venous system. Properties of Heart Muscle. Action of Heart and Heart Beat. Blood Pressure. Lymph and Lymphatic system. 06 Hours

UNIT 3:
DIGESTIVE SYSTEM
Overview of digestive system, functional anatomy of digestive system: mouth, pharynx, esophagus, the stomach the small and large intestine. Digestive glands, Enzymes; Physiology of Digestion and Absorption. Energy requirements of the body. 06 Hours

UNIT 4:
RESPIRATORY SYSTEM
Introduction; structure of respiratory organs; Mechanism of breathing; Pulmonary air volumes, Gas exchange in the lungs; respiratory adjustments in exercise, Artificial respiration; Kinds of respiration; Transport of respiratory gases in the blood; Cellular respiration; Respiratory quotient; Some respiratory disorders; Control of respiration. 07 Hours

PART B

UNIT 5:
EXCRETORY SYSTEM
Methods of excretion; Physiological processes involved in excretion; Kidneys; Anatomy and physiology, Nephron and its structure. Functions of nephron; Nephron physiology and mechanism of urine formation; Regulation of urine formation; Osmoregulation by kidney. 06 Hours

UNIT 6:
NERVOUS SYSTEM
Introduction; Role of nervous system; Generalized neuron; Morphological types of neurons; Physiological or functional types of neurons; Main properties of nervous tissue; Stimulus; Mode of action of nerves; Conduction of nerve impulses; Reflex action; Central nervous system; The brain; The spinal cord; Peripheral nervous system and reflux activity. Special senses: tounge, smell, eye, hearing and balance. 10 Hours

UNIT 7:
ENDOCRINE SYSTEM
Introduction; Endocrine systems of vertebrates; Pituitary gland; Thyroid gland; Parathyroid gland; Pancreas; Adrenal or suprarenal glands; Sex glands; Gastrointestinal mucosa; Thymus gland; Pineal gland; Summary of different endocrine glands; their hormones and influence; Summary of the effect of hyper secretion and hyposecretion of some important endocrine glands; 06 Hours

UNIT 8:
REPRODUCTIVE SYSTEM
Physiology of male and female reproduction systems, invitro fertilization, fertility in males and females, factors influencing fertility, test tube baby, sperm count, preservation of sperms. 04 Hours

TEXT BOOK:
Textbook of medical physiology by Arthur C Guyton, Saunders College Publishing.
Ross & Wilson’s Anatomy and Physiology in Health and Illness – by Anne Waugh and Allison Grant, Churchill Livingstone Publications.
Essentials of Medical Physiology – by K. Sembulingam and Prema Sembulingam, Jaypee Publications.
Text book of Human Physiology by Chakraborthy & Ghosh, Paramount Pub.
A Text Book oh Human Physiology by H S Ravikumar Patil, IK Intl. Publishing

REFERENCE BOOKS:
Human Anatomy & Physiology by Marieb, Pearson Education.
Concise Medical Physiology- by Sujit K. Chaudhuri, New Central Book Agency Pvt. Ltd.

BIOCHEMISTRY
Subject code : 10BT-34

I.A Marks : 25
Hrs./Week : 04 Exam Hrs. : 03
Total Hours : 52 Exam Marks : 100

PART A

UNIT 1:
BASIC CONCEPTS
Types of chemical reactions, pH, buffers and their properties, concentration of solutions. Stereo chemistry of carbon compounds. 04 Hours

UNIT 2:
BIOMOLECULES
Carbohydrates, fats and lipids, structure and properties of phospholipids, glycolipids, steroids, amino acids and proteins. Biologically important peptides, purines, pyrimidines, nucleic Acids- DNA and RNA. 06 Hours

UNIT 3:
BIOENERGETICS
Energy, energy flow cycle, energy conversion. Structure and properties of ATP. High energy compounds, Thermodynamic considerations, Coupling reactions of ATP and NDP (Nucleotide di phosphate); photosynthesis, ancillary Pigments, Photosystems PS I & II; 08 Hours

UNIT 4:
TRANSPORT MECHANISM
Biological membranes: structure, permeability, properties, passive transport and active transport, facilitated transport, energy requirement, mechanism of Na+ / K+, glucose and amino acid transport. Organization of transport activity in cell. Action Potentials. Role of transport in signal transduction processes. 08 Hours

PART B

UNIT 5:
CARBOHYDRATE METABOLISM
Glycolysis –metabolism. Aerobic and anaerobic pathway and regulation, TCA cycle, NADPH Cycle, Calvin Cycle, Glyoxylate cycle, Pentose Phosphate Pathway. Electron transport chain and oxidative phosphorylation, energetics, energy balance sheet, oxidative stress. Gluconeogenesis – regulation of gluconeogenesis. Biosynthesis of polysaccharides. Disorders of carbohydrate metabolism. 10 Hours

UNIT 6:
LIPID METABOLISM
Biosynthesis of fatty acids, cholesterol, phospholipids, glycolipids. Biodegradation of triglycerides and fatty acids. Disorders of Lipid metabolism. 05 Hours

UNIT 7:
AMINO ACID METABOLISM
Biosynthesis of essential amino acids: Lysine, Phenylalaninine and Glutamine. Biodegradation of amino acids, deamination, transamination and urea cycle. Disorders of amino acid metabolism. 06 Hours

UNIT 8:
NUCLEIC ACID METABOLISM
Biosynthesis, biodegradation, and regulation of Purines, pyrimidines and precursors of nucleic acids (nucleosides & nucleotides). Disorders of nucleic acid metabolism. 05 Hours

TEXT BOOKS
Principles of Biochemistry by Albert Lehninger, CBS publishers
Biochemistry by Nelson and Cox, Palgrave Macmilan, Freeman Edn.
Principles of Biochemistry by Lubert Stryer, Freeman Int. Edition
Biochemistry by Mathews, Vanholde & Arhen, Pearson Education.
Biochemistry by Garett & Grisham Thompson Learning.
Bioenergetics by L Eruster, Greena Publishing Associates.

REFERENCE BOOKS
Biochemistry by Voet & Voet, Wiley New York.
Biochemistry by Trehan. K, New Age International.
Biochemistry & Molecular Biology by Elliot, William H., Oxford University Press.
Biochemistry of cell signaling by Helmreich, Oxford University Press.
Bioorganic Chemistry by Hermann Dugas, Spinger.
Biochemistry by U Sathyanarayana, Books & Allied Publishers.
Bioenergetics and its thermodynamics foundations by Lars Garby and Poul S Larsen, Cambridge University Press.

MICROBIOLOGY
Subject code : 10BT-35

I.A Marks : 25
Hrs./Week : 04 Exam Hrs. : 03
Total Hours : 52 Exam Marks : 100

PART A

UNIT 1:
INTRODUCTION
Scope of microbiology, History of microbiology, Origin of life, Prokaryotes and Eukaryotes. Microbial Diversity and Taxonomy. 05 Hours

UNIT 2 :
METHODS IN MICROBIOLOGY
Sterilization & disinfection, Microscopy: Concepts, Light, Electron, Phase Contrast, Acoustic Microscopy, camera Lucida and Micrometry. 06 Hours

UNIT 3:
MICROORGANISMS
Structure, Classification and Reproduction of bacteria, Fungi, Viruses, Protozoa and Algae. General features of Prions, Spirochetes, Actinomycetes and Rickettsiae. 08 Hours

UNIT 4:
MICROBIAL GROWTH AND METABOLISM
Growth curve, Physical conditions required for growth. Metabolism; Primary and Secondary metabolites, metabolic pathways important in Microorganisms. 07 Hours

PART B

UNIT 5:
MEDICAL MICROBIOLOGY
Introduction to Medical Microbiology, Common diseases caused by microbes: Bacterial diseases: Typhoid, Diphtheria, Tuberculosis, Leprosy, Plague; Viral diseases: Herpes, Polio, Hepatitis, AIDS, Rabies, SARS and H1N1; Protozoal diseases: Syphilis, Gonorrhea, and Malaria. 08 Hours

UNIT 6:
SOIL MICROBIOLOGY
Soil micro flora and biogeochemical cycles. Biofertilizers: VAM and Rhizobium. 06 Hours

UNIT 7:
ENVIRONMENTAL MICROBIOLOGY
Atmospheric Microbiology: Aerobiology and allergy. Air sampling principles and samplers, Selective media for air sampling, Identification of spores/pollens, spore count, significance of aerobiological studies. 04 Hours
Aquatic Microbiology: Marine micro flora, fresh water microflora, Microbiology of potable water, Purification, Sewage disposal, Microbes in Bioremediation. 04 Hours

UNIT 8:
INDUSTRIAL MICROBIOLOGY
Production of antibiotics, Organic acids, Enzymes from Microbes (including scope) 04 Hours

REFERENCES
Refer Syllabus Copy

CELL BIOLOGY & GENETICS
Subject code : 10BT-36

I.A Marks : 25
Hrs./Week : 04 Exam Hrs. : 03
Total Hours : 52 Exam Marks : 100

PART A

UNIT 1:
CYTOSKELETON
Eukaryotic and prokaryotic cells, Plant and animal cells, brief mention of membrane organization. Cytosketal elements, Microtubules: structure & functions, shaping of the cells and mechanical support. Microfilaments: structure & functions. Structure of intermediate filaments. Cytoplasmic microtrabecular system (lattice). Covalent modifications of cytosketal proteins. Cytoskeletal architechture. 08 Hours

UNIT 2:
CELL STRUCTURE AND FUNCTION
Mitosis and Meosis. Structure of cytolplasm, Nucleus, Mitochondria, Ribosome, Golgi bodies, Lysosomes. Endoplasmic Reticulum, Peroxisomes, Chloroplast and Vacuoles. Cell to cell integration, Cell locomotion (Ameoboid, Flagella, Cillar).Types of cell functions, cell division. 08 Hours

UNIT 3:
HAEMOTOLOGY
Components of blood plasma cell (R B C, W B C, Platelets) Hemopioesis, Erythropoiesis, Leucopoiesis. 04 Hours

UNIT 4:
GROWTH FACTORS
Structure, Mechanism, Action of receptors (cytosolic, Nuclear, Membrane bound receptors) Autocrine, paracrine, Endocrine models, Action, Characterization of receptors. Structure and physiological function of Plant growth regulators – Auxins, Gibberlins, Cytokinins, Abscisic acid and ethylene. 06 Hours

PART B

UNIT 5:
GENETICS
Nature of genetic material, Mendelian Laws of inheritance, monohybrid and dihybrid inheritance, law of segregation & independent assortment, Gene interactions, supplementary genes – Comb patterns in fowls, Complementary genes – Flower colour in sweet peas, Epistasis10 Inhibitory and coloured genes in fowls, simple problems. Identification of genetic material, classical experiments- Hershey & Chase, Avery, McLeod etc., Multiple alleles and groups antigens. Conceptual numericals. 08 Hours

UNIT 6:
CHROMOSOMES STRUCTURE AND ORGANIZATION
Chromosome, Centrosome, telomere, Chemical composition of chromatin, structural organization of nucleosomes, heterochromatin. Polytene and lamp-brush chromosomes, human chromosomes. 06 Hours

UNIT 7:
SEX CHROMOSOMES AND INHERITED DISEASES
The organ of heredity, chromosomes, morphology, classification. Sex determination in plants, animals XX-XY, XX-XO, ZW-ZZ, ZO-ZZ types in animals. Chromosomal disorders. Sex linked inheritance molecular diseases, hemoglobinopathies. Disorders of coagulation, Colour blindness, hemophilia, Non-disjunction as a proof of chromosomal theory of inheritance, Linkage maps, crossing over. Chromosomal maps, interference coincidence. 08 Hours

UNIT 8:
POPULATION GENETICS
Introduction, Gene frequency, and equilibrium estimation, changes in gene frequency, inbreeding and heterosis, genetic structure of population, speciation and evolution, prospects for the control of human evolution. Spontaneous and induced mutations, Eugenics. Pedigree analysis.04 Hours

TEXT BOOKS
Cell Biology by Kimbal, Willey Pub.
Cell Biology by S C Rastogi, New Age International Pub.
Genetics by Monroe W Strickberger, Macmillan Pub. Newyork.
Principles of Genetics by Gardener, Simmons and Slustad. Wiley Pub.
Principles of Gene manipulation and Genomics by Primrose, Oxford University Press.
Genetics W Strick by Monroe, Macmillan Pub

REFERENCE BOOKS
Molecular Cell Biology by Darnell, and Baltimore, Freeman Pub.
Molecular Aspects of Cell Biology by Garret and Grisham. Cengage Learning.
Cellular & Biochemical Science by G. Tripathi, I K Intl.
Genes and Genomes by M Singer, and P Berg, Blackwell Scientific Pub.
Developmental Genetics by Gurbachan s & Miglani, I K Intl. Pub.
Problems on Genetics, Molecular Genetics and Evolutionary Genetics by Pranab Kr. Banerjee, New Central Book Agency.

BIOCHEMISTRY LABORATORY
Subject code : 10BTL-37

I.A Marks : 25
Hrs./Week : 03 Exam Hrs. : 03
Exam Marks : 50

  • 1. pH measurements, volume / weight measurements, concentration units, sensitivity Specificity, precision, accuracy, preparation of buffers of constant strength.
  • 2. Titration of amino acids with acids & bases.
  • 3. Qualitative tests for carbohydrate and lipids.
  • 4. Qualitative tests for amino acids and proteins.
  • 5. Estimation of blood sugar by Folin method.
  • 6. Estimation of blood sugar by O-toluene method.
  • 7. Estimation of inorganic phosphate by Fiske-Subbarao method.
  • 8. Estimation of amino acid by ninhydrin method.
  • 9. Estimation of total cholesterol from Serum.
  • 10. Determination of Saponification value of lipids.
  • 11. Determination of Iodine value of lipid.
  • 12. Determination of acetyl value of a lipid.
  • 13. Estimation of urea by diacetyl monooxime method.
  • 14. Estimation of iron from hemoglobin.
  • 15. Error Analysis (mandatory for Experiments under Sl. No. 10 -14)

REFERENCE BOOKS
Refer Syllabus Copy

UNIT OPERATIONS LABORATORY
Sub. Code : 10BTL-38

IA Marks : 25
Hrs/Week : 03 Exams Hrs : 03
Exam Marks : 50

  • 1. Friction in circular and non circular pipes.
  • 2. Flow rate measurement using orificemeter
  • 3. Flow rate measurement using Venturimeter.
  • 4. Determination of minimum thickener area using Batch sedimentation tests.
  • 5. Constant pressure filtration using leaf filter.
  • 6. Verification of Stoke’s law in Free Settling.
  • 7. Determination of effectiveness of a screen
  • 8. Sieve analysis – differential and cumulative.
  • 9. Critical thickness of insulation.
  • 10. Vertical condenser / Horizontal condenser.
  • 11. Heat transfer in packed bed.
  • 12. Diffusion of organic solvent in air.
  • 13. Simple Distillation.
  • 14. Steam Distillation.
  • 15. Liquid – liquid Extraction.
  • 16. Study of pump Characteristics.
  • 17. Leaching studies.

REFERENCE BOOKS
Refer Syllabus Copy

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